Gatorade
Gatorade® Becomes a Reality
Dr. Matt Hermes


Dr. Robert Cade's group at the University of Florida understood their football coaches had tried orange juice or a sugar-containing soft drink to quench the thirst and supply fluids during summer football practice. Orange juice and soft drinks offer taste and tang; most people like to drink them. We might expect juice or soft drinks would function well to provide rehydration during exercise. But two things happened. The athletes felt full, the beverages didn't seem to slake their thirst. And if they drank too much juice or soft drink, many of the exercising athletes felt ill. They suffered the inconvenience of vomiting and diarrhea.


Dr. Cade and his associates began with the salt solution used for intravenous replacement of fluids in the body. Then they added glucose for energy. Glucose is the sugar that provides energy most rapidly but is not sweet.  A few athletes tried this concoction but reported it was undrinkable.

The physicians quickly learned that they would have to combine the energy-producing sugars and the salts in a beverage that was enjoyable to drink. That it would do no good if their composition was suitable to provide energy and replenish salts but was not palatable to the athlete in the course of his or her exercise.   Generally, we are attracted to beverages that are cold, have some sweetness but are tart, with the bite of citrus.  We add a slice of lemon or lime to many beverages to get this effect

So the doctors reformulated their beverage.  They added the artificial sweetener, cyclamate to the formulation. And finally, they chose to incorporate some citric acid -- the chemical responsible for the tartness of citric juices.

Cyclamate artificial sweetener was discovered in 1937. As we will soon see, it was banned from use in beverages in the United States in 1970 because of testing that linked the substance with cancer in test animals. Nevertheless, the compound is made for consumption in other parts of the world

The reformulated composition contained a slightly higher concentration of dissolved particles per liter that we find in the body.  The inventors reasoned most athletes would put ice in the drink and dilute it down to the approximate concentration of body fluid.

This formulation worked.  Athletes would drink it.   It provided energy and salt replenishment. The invention became Gatorade®, after the tremendous aid it had provided University of Florida, whose team mascot is the (alli)Gator.

Chemical Concepts
The formulation of Gatorade® depended on detailed consideration of the properties of near-isotonic solutions.

8. Isotonic Solutions are Solutions Containing the Same Concentration of Particles
Essential in Human Sysytems to Prevent Cell Crenation (Shriveling) or Hemolysis (Swelling)
Difficult to Maintain in the Exercising Athlete

Try to relate these concepts to the relationship of exercise, dehydrationand fatigue that we discuss in the accompanying unit.

 

 

©2003 Kennesaw State University
Principal Investigator Laurence Peterson
Project Director Matthew Hermes