Olestra
Nat Cooper

 

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Ahead to Olestra 2. Food and Biomolecules

Chemical Concepts
Our  emphasis will be on three concepts of chemistry in this Olestra unit. 

Energy available can be determined from The type and amount of food we eat
Enzymes enable our bodies to metabolize foods
Intermolecular forces explain the fate of fats, fat substitutes and vitamins in our bodies

We will see how researchers used these simple chemical concepts to invent and develop olestra and we will use these principles ourselves to evaluate and decide on nutritional issues

Micro/Macro
and Symbolic
Representation

Remember that chemistry uses macroscopic, large scale observation to help describe and understand matter at the unseeable, molecular level. 

Then, we use what we believe are valid molecular predictions to postulate new behavior at the observable level.  You will see in this unit how Proctor&Gamble scientists observed, then postulated in the development of olestra.

And one final note:  perhaps the most difficult thing about chemistry is that we have to find ways to represent both macroscopic and molecular phenomena.  Pay close attention to how we do that.  We use many conventions of notation.   Sometimes a carbon atom is a capital "C", sometimes it is a sphere, sometimes other representations are used.  Be aware that a vivid imagination is essential in unraveling these representations developed by chemists over the last three centuries!

  Olestra 1. Introduction

Food is a major part of all of our lives. We spend countless hours thinking, preparing, and enjoying all types of food from the quick snack to the holiday feast. This ChemCases.com unit will help you learn more about all food molecules, their digestion, and a new fat replacement molecule, Olestra, which has been developed by the Procter and Gamble Corporation.

Olestra is available in many snack foods such as chips, crackers, popcorn and cheese puffs. Let's begin by looking at some information on the typical American diet and how this creates a possible need for fat substitutes in our diet.

Roughly 30 % of all Americans are overweight and this obesity is a major public health problem, second only to cigarette smoking as an avoidable cause of death. Diet, of course, plays a major role in this. Food, as it supplies all of our dietary needs, can be thought of as proteins, carbohydrates, fats, vitamins and minerals. While we get many of our daily calories from carbohydrates and proteins, the most concentrated supplier of calories is fat with 9 kcal (remember that a food calorie is actually 1000 calories from your chemistry class) per gram. In addition, most of us like to eat fat rich foods- in our ice cream, our chips, our other dairy products, and many other food sources. This "fat Tooth" that many of us have may be an evolutionary holdover from the early cycle of feast and famine that we faced as a species. Today, though, fatty foods are everywhere and this has resulted not only in obesity, but other life shortening diseases such as heart disease, vascular disease, and cancer.  You might look at some information on foods and food research.

Numerous health organizations (see http://www.shapeup.org and others) have recommended that Americans reduce their total dietary intake of calories, fat, and the particular types of fat that we eat. In later sections, we will study the basic about fats, including the different types such as saturated, unsaturated, hydrogenated fats that contain potentially harmful trans-fatty acids, and how all of these relate to serum cholesterol levels in your blood.

We will take a detailed look at the chemistry of the dietary fat replacement molecule Olestra. We will learn why Olestra tastes like a fat, feels like a fat, cooks like a fat, but provides no calories. This story also has interesting aspects because of the original development of Olestra as a cholesterol lowering drug nearly three decades ago, and the current controversies surrounding Olestra regarding possible vitamin and mineral depletion and digestion problems.

For now though, head back to the Olestra Concept Map and begin your adventure in Chemistry!


Bread and Cheese: Carbohydrate and Fat Rich Foods

College of Science and Mathematics
Kennesaw State University
1000 Chastain Rd.
Kennesaw, GA 30114
770-423-6160